Every Which Way but Loose (1978)

Philo Beddoe is your regular, easygoing, truck-driving guy. He's also the best bar-room brawler west of the Rockies. And he lives with a 165-pound orangutan named Clyde. Like other guys, Philo finally falls in love - with a flighty singer who leads him on a screwball chase across the American Southwest. Nothing's in the way except a motorcycle gang, and legendary brawler Tank Murdock.